Detalhe da pesquisa
1.
GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Nature
; 619(7968): 143-150, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37380764
2.
Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.
Proc Natl Acad Sci U S A
; 118(27)2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187898
3.
Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals.
Am J Physiol Endocrinol Metab
; 321(4): E443-E452, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34370594
4.
GDF15 increases insulin action in the liver and adipose tissue via a ß-adrenergic receptor-mediated mechanism.
Cell Metab
; 35(8): 1327-1340.e5, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37473755
5.
AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance.
J Biol Chem
; 285(1): 115-22, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19892703
6.
GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease.
Nat Rev Endocrinol
; 17(10): 592-607, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381196
7.
Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation.
Am J Physiol Endocrinol Metab
; 297(1): E57-66, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19435854
8.
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
J Physiol
; 586(23): 5819-31, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18845612
9.
How is AMPK activity regulated in skeletal muscles during exercise?
Front Biosci
; 13: 5589-604, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18508608
10.
The AMP-activated protein kinase: role in regulation of skeletal muscle metabolism and insulin sensitivity.
Mini Rev Med Chem
; 7(5): 519-26, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17504187
11.
Central regulation of the anorexigenic receptor GFRAL.
Nat Metab
; 4(2): 157-158, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35177852
12.
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
Nat Med
; 23(10): 1158-1166, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846099
13.
The anorectic actions of the TGFß cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract.
PLoS One
; 9(6): e100370, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24971956
14.
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity.
Diabetes
; 62(1): 56-64, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961088
15.
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator.
PLoS One
; 8(2): e55174, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468844
16.
Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase-dependent pathway that is impaired with obesity.
Diabetes
; 58(4): 829-39, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19136654